NCLEX Review For Drug Intoxication

Nephrotoxic (Damage to the Kidneys)


 acetaminophen (high dose, acute)
 acyclovir, parenteral (Zovirax)
 aminoglycosides
 amphotereric B, parenteral (Fugizone)
 ciprofloxacin
 cisplatin (Platinol)
 methotrexate (high dose)
 NSAIDS
 Rifampin
 Sulfonamides
 Tetracyclines (except doxycycline & minocycline)
 vancomycin, parenteral (Vancocin)
 ancef (Cefazolin)
 bactrim (Co-trimoxazole)
 Ca Edta (Edetate Calcium Sodium)
 analgesic combinations containing acetaminophen, aspirin, or other salicylates in high doses, chronically

Ototoxic (Hearing and Inner Ear Damage) aminoglycosides
 bumetanide, parenteral (Bumex)
 cisplatin (Platinol)
 erythromycin (renal impairment in high doses)
 ethacrynic acid (Edecrin)
 furosemide (Lasix)
 hydrochloroquine (Plaquenil)
 NSAIDs
 salicylates (chronic high doses, overuse)
 vancomycin, parenteral (high doses and renal impairment)



Hepatotoxic (Damage to the liver)

 ACE inhibitors
 Acetaminophen
 alcohol
 iron overdose
 erythromycins
 estrogens
 fluconazole (Diflucan)
 isoniazid (INH)
 itraconazole (Sporanox)
 ketoconazole (Nizoral)
 NSAIDS
 phenothiazines
 phenytoin (Dilantin)
 rifampin (Rifadin)
 sulfamethoxazole & trimethoprin (Bactrim, Septra)
 sulfonamides
 Valproic Acid (Depakene)